ATG12 antibody
GTX124181
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetATG12
Overview
- SupplierGeneTex
- Product NameATG12 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.43 mg/ml
- ConjugateUnconjugated
- Gene ID9140
- Target nameATG12
- Target descriptionautophagy related 12
- Target synonymsAPG12; Apg12 (autophagy, yeast) homolog; APG12 autophagy 12-like; APG12L; ATG12 autophagy related 12 homolog; FBR93; HAPG12; ubiquitin-like protein ATG12
- HostRabbit
- IsotypeIgG
- Protein IDO94817
- Protein NameUbiquitin-like protein ATG12
- Scientific DescriptionAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Scanning Electron-Assisted Dielectric Microscopy Reveals Autophagosome Formation by LC3 and ATG12 in Cultured Mammalian Cells. Okada T et al., 2021 Feb 12, Int J Mol SciRead more
- Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling. Ho KH et al., 2021 Apr, NeurotherapeuticsRead more
- BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Lin TY et al., 2020 Jul, AutophagyRead more
- In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. Chen JC et al., 2019 Sep 9, BiomoleculesRead more
- Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor-1 Alpha Pathway in Non-Small Cell Lung Cancer Cells. Hsu HL et al., 2019 Jan 3, Int J Mol SciRead more
- Helicobacter pylori cholesterol glucosylation modulates autophagy for increasing intracellular survival in macrophages. Lai CH et al., 2018 Dec, Cell MicrobiolRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Koh EH et al., 2018 Dec, DiabetesRead more
- Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy. Kuo SM et al., 2017 Jun 13, MBioRead more
- Fisetin Protects PC12 Cells from Tunicamycin-Mediated Cell Death via Reactive Oxygen Species Scavenging and Modulation of Nrf2-Driven Gene Expression, SIRT1 and MAPK Signaling in PC12 Cells. Yen JH et al., 2017 Apr 17, Int J Mol SciRead more
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