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ATG4B Antibody, Biotin conjugated

Research Use Only
CSB-PA002290LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetATG4B
Price on request
Packing Size
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Overview

  • Supplier
    Cusabio
  • Product Name
    ATG4B Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID23192
  • Target name
    ATG4B
  • Target description
    autophagy related 4B cysteine peptidase
  • Target synonyms
    APG4 autophagy 4 homolog B; APG4B; ATG4 autophagy related 4 homolog B; AUTL1; AUT-like 1 cysteine endopeptidase; autophagin-1; autophagy-related cysteine endopeptidase 1; autophagy-related protein 4 homolog B; cysteine protease ATG4B; hAPG4B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y4P1
  • Protein Name
    Cysteine protease ATG4B
  • Scientific Description
    Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203