ATG4B Antibody, Biotin conjugated
CSB-PA002290LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetATG4B
Overview
- SupplierCusabio
- Product NameATG4B Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID23192
- Target nameATG4B
- Target descriptionautophagy related 4B cysteine peptidase
- Target synonymsAPG4 autophagy 4 homolog B; APG4B; ATG4 autophagy related 4 homolog B; AUTL1; AUT-like 1 cysteine endopeptidase; autophagin-1; autophagy-related cysteine endopeptidase 1; autophagy-related protein 4 homolog B; cysteine protease ATG4B; hAPG4B
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y4P1
- Protein NameCysteine protease ATG4B
- Scientific DescriptionCysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203