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ATG7 antibody [N3C2], Internal

Name: ATG7 antibody [N3C2], Internal
SKU: GTX113613_G10
Availability: BackOrder

GTX113613

ApplicationsWestern Blot

Product group Antibodies

TargetATG7

Overview

Supplier
GeneTex
Product Name
ATG7 antibody [N3C2], Internal
Delivery Days Customer
9
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID10533
Target name
ATG7
Target description
autophagy related 7
Target synonyms
APG7-LIKE, APG7L, GSA7, SCAR31, ubiquitin-like modifier-activating enzyme ATG7, APG7 autophagy 7-like, ATG12-activating enzyme E1 ATG7, hAGP7, ubiquitin-activating enzyme E1-like protein
Host
Rabbit
Isotype
IgG
Protein IDO95352
Protein Name
Ubiquitin-like modifier-activating enzyme ATG7
Scientific Description
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Palanisamy K, Tsai TH, Yu TM, et al. RNA-binding protein, human antigen R regulates hypoxia-induced autophagy by targeting ATG7/ATG16L1 expressions and autophagosome formation. J Cell Physiol. 2019,234(5):7448-7458. doi: 10.1002/jcp.27502
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Chang HP, Lu CC, Chiang JH, et al. Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. Int J Oncol. 2018,52(5):1504-1514. doi: 10.3892/ijo.2018.4298
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Bechor S, Nachmias D, Elia N, et al. Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux. Biochim Biophys Acta Mol Cell Biol Lipids. 2017,1862(9):1001-1012. doi: 10.1016/j.bbalip.2017.06.012
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Chi HC, Chen SL, Tsai CY, et al. Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy. Autophagy. 2016,12(12):2271-2285.
Read this paper
Matsuzawa T, Fujiwara E, Washi Y. Autophagy activation by interferon-γ via the p38 mitogen-activated protein kinase signalling pathway is involved in macrophage bactericidal activity. Immunology. 2014,141(1):61-9. doi: 10.1111/imm.12168
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Matsuzawa T, Kim BH, Shenoy AR, et al. IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol. 2012,189(2):813-8. doi: 10.4049/jimmunol.1102041
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