ATM Inhibitor-1 [2135639-94-8]

TargetMol Chemicals

ATM Inhibitor-1

114

2135639-94-8

Chemical

Research Use Only

ATM Inhibitor-1

C27H36N6O3

492.61

ATM Inhibitor-1 is a highly potent, selective, and orally active ATM inhibitor (IC50: 0.7 nM) with anti-tumor activity. It exhibits weak activity against mTOR (IC50, 21 microM), DNAPK (IC50, 2.8 microM), PI3Kalpha (IC50, 3.8 microM), PI3Kbeta (IC50, 10.3 microM), PI3Kgamma (IC50, 3 microM), and PI3Kdelta (IC50, 0.73 microM).

3 years

N([C@@H](C)C1CCOCC1)C=2C3=C(N=NC2C(NC)=O)C=CC(=C3)C=4C=CC(OCCCN(C)C)=NC4

-20°C

51202000