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ATP6V1B2 antibody

Research Use Only
GTX110783
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP6V1B2
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATP6V1B2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID526
  • Target name
    ATP6V1B2
  • Target description
    ATPase H+ transporting V1 subunit B2
  • Target synonyms
    ATP6B1B2; ATP6B2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; DOOD; endomembrane proton pump 58 kDa subunit; H+ transporting two-sector ATPase; HO57; testicular secretory protein Li 65; vacuolar H+-ATPase 56,000 subunit; vacuolar proton pump subunit B 2; VATB; V-ATPase B2 subunit; V-ATPase subunit B 2; Vma2; VPP3; V-type proton ATPase subunit B, brain isoform; ZLS2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP21281
  • Protein Name
    V-type proton ATPase subunit B, brain isoform
  • Scientific Description
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation. Hong J et al., 2019 Oct 25, Cancers (Basel)
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