Bio-Connect

AUF1 antibody

GTX101814
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetHNRNPD
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Overview

  • Supplier
    GeneTex
  • Product Name
    AUF1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.45 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3184
  • Target name
    HNRNPD
  • Target description
    heterogeneous nuclear ribonucleoprotein D
  • Target synonyms
    ARE-binding protein AUFI, type A; AUF1; AUF1A; AU-rich element RNA binding protein 1, 37kDa; heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; hnRNPD0; HNRPD; P37
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14103
  • Protein Name
    Heterogeneous nuclear ribonucleoprotein D0
  • Scientific Description
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP). Hwang CK et al., 2017 Jan 20, Gene
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