AUF1 antibody
GTX101814
Overview
- SupplierGeneTex
- Product NameAUF1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.45 mg/ml
- ConjugateUnconjugated
- Gene ID3184
- Target nameHNRNPD
- Target descriptionheterogeneous nuclear ribonucleoprotein D
- Target synonymsARE-binding protein AUFI, type A; AUF1; AUF1A; AU-rich element RNA binding protein 1, 37kDa; heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; hnRNPD0; HNRPD; P37
- HostRabbit
- IsotypeIgG
- Protein IDQ14103
- Protein NameHeterogeneous nuclear ribonucleoprotein D0
- Scientific DescriptionThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP). Hwang CK et al., 2017 Jan 20, GeneRead more