Autophinib

AbMole BioScience

Autophinib

9

1644443-47-9

Chemical

Research Use Only

C14H11ClN6O3

346.73

Autophinib is a novel potent autophagy inhibitor, inhibiting autophagy induced by starvation or Rapamycin with IC50 values of 90 and 40 nM, targeting the lipid kinase VPS34 with IC50 value of 19 nM in vitro.

CC1=CC(=N[NH]1)NC2=CC(=NC(=N2)OC3=CC=C(C=C3)[N+]([O-])=O)Cl

12352200