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Avadomide

M14326
AbMole BioScience
CAS Number1015474-32-4
Product group Chemicals
Molecular Weight286.29
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Avadomide
  • Delivery Days Customer
    9
  • CAS Number
    1015474-32-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Weight
    286.29
  • Scientific Description
    Avadomide (CC 122) is an orally effective cereblon modulator. avadomide modulates cereblon E3 ligase activity and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cells. Avadomide has antitumor and immunomodulatory activities. CC-122 is more potent in degrading IKZF1 and IKZF3 than lenalidomide and has broader and enhanced antiproliferative activity in ABC- and GCB-DLBCL cell lines.
  • SMILES
    CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N
  • UNSPSC
    12352200

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