Avagacestat
HY-50845
CAS Number1146699-66-2
Product group Chemicals
Estimated Purity99.89
Molecular Weight520.89
Overview
- SupplierMedChem Express
- Product NameAvagacestat [1146699-66-2]
- Delivery Days Customer5
- CAS Number1146699-66-2
- CertificationResearch Use Only
- Estimated Purity99.89
- Molecular FormulaC20H17ClF4N4O4S
- Molecular Weight520.89
- Scientific DescriptionAvagacestat (BMS-708163) is a potent inhibitor of gamma-secretase , with IC 50 s of 0.27 nM and 0.30 nM for Abeta42 and Abeta40 inhibition; Avagacestat (BMS-708163) also inhibits NICD (Notch IntraCellular Domain) with IC 50 of 0.84 nM and shows weak inhibition of CYP2C19, with IC 50 of 20 microM. Avagacestat can be used for Alzheimer disease research.
- SMILESO=S(N([C@@H](C(N)=O)CCC(F)(F)F)CC1=CC=C(C2=NOC=N2)C=C1F)(C3=CC=C(Cl)C=C3)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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AvagacestatORB1300938
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![Avagacestat [1146699-66-2]](https://www.targetmol.com/group3/M00/35/73/CgoaEWayH_CEWmz8AAAAAMdHPI0566.png)
Product group Chemicals
CAS Number1146699-66-2
Estimated Purity99.77%
Molecular Weight520.89
- SizePrice
