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Avagacestat [1146699-66-2]

Avagacestat [1146699-66-2]

T6249
TargetMol Chemicals
CAS Number1146699-66-2
Product group Chemicals
Estimated Purity99.77%
Molecular Weight520.89
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Avagacestat [1146699-66-2]
  • Delivery Days Customer
    9
  • CAS Number
    1146699-66-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Avagacestat
  • Estimated Purity
    99.77%
  • Molecular Formula
    C20H17ClF4N4O4S
  • Molecular Weight
    520.89
  • Scientific Description
    Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
  • Shelf life instruction
    3 years
  • SMILES
    NC(=O)[C@@H](CCC(F)(F)F)N(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200