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ProductsBack/Avatrombopag (hydrochloride) [570403-17-7]

Avatrombopag (hydrochloride) [570403-17-7]

HY-13463B
MedChem Express
CAS Number570403-17-7
Product group Chemicals
Estimated Purity97.05
Molecular Weight686.12
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Avatrombopag (hydrochloride) [570403-17-7]
  • Delivery Days Customer
    5
  • CAS Number
    570403-17-7
  • Certification
    Research Use Only
  • Estimated Purity
    97.05
  • Molecular Formula
    C29H35Cl3N6O3S2
  • Molecular Weight
    686.12
  • Scientific Description
    Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].
  • SMILES
    O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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