Avatrombopag hydrochloride [570403-17-7]
T40654
CAS Number570403-17-7
Product group Chemicals
Overview
- SupplierTargetMol Chemicals
- Product NameAvatrombopag hydrochloride [570403-17-7]
- Delivery Days Customer999
- CAS Number570403-17-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameAvatrombopag hydrochloride
- Scientific DescriptionAvatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC50 of 3.3 nM. It effectively mimics TPO by stimulating platelet production through activation of the intracellular signaling system, facilitating platelet and megakaryocyte generation from hemopoietic precursor cells. Additionally, Avatrombopag hydrochloride serves as a substrate for cytochrome P450 [CYP] 2C9 and CYP3A.
- Shelf life instruction3 years
- SMILESCl.OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(-c2cc(Cl)cs2)c(s1)N1CCN(CC1)C1CCCCC1
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number570403-17-7
Estimated Purity97.05
Molecular Weight686.12
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Avatrombopag hydrochlorideORB1089415
CAS Number570403-17-7
Molecular Weight686.12
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Molecular Weight686.12
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