AY 9944 [366-93-8]
T14362
CAS Number366-93-8
Product group Chemicals
Estimated Purity99.65%
Molecular Weight464.3
Overview
- SupplierTargetMol Chemicals
- Product NameAY 9944
- Delivery Days Customer4
- CAS Number366-93-8
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameAY 9944
- Estimated Purity99.65%
- Molecular FormulaC22H30Cl4N2
- Molecular Weight464.3
- Scientific DescriptionAY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol delta7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 also inhibits sterol delta7-delta8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3beta-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
- Shelf life instruction3 years
- SMILESCl.Cl.Clc1ccccc1CNC[C@H]1CC[C@H](CNCc2ccccc2Cl)CC1
- Storage Instruction-20°C
- UNSPSC12352200
