AZ-5104

MedChem Express

AZ-5104 [1421373-98-9]

10

1421373-98-9

Research Use Only

99.69

C27H31N7O2

485.58

AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC 50 s of 1, 6, 1, 25 and 7 nM for EGFR L858R/T790M , EGFR L858R , EGFR L861Q , EGFR and ErbB4, respectively.

C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O

-20°C,2°C to 8°C

12352200