AZ5104
M4977
CAS Number1421373-98-9
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight485.58
Overview
- SupplierAbMole BioScience
- Product NameAZ5104
- Delivery Days Customer9
- CAS Number1421373-98-9
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity>99.0%
- Molecular FormulaC27H31N7O2
- Molecular Weight485.58
- Scientific DescriptionAZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively.
- SMILESCOC1=C(NC2=NC=CC(=N2)C3=C[NH]C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C
- UNSPSC12352200