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AZ3976

M28380
AbMole BioScience
CAS Number1418747-15-5
Product group Chemicals
Molecular Weight317.34
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    AZ3976
  • Delivery Days Customer
    9
  • CAS Number
    1418747-15-5
  • Certification
    Research Use Only
  • Molecular Formula
    C15H19N5O3
  • Molecular Weight
    317.34
  • Scientific Description
    AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 uM in an enzymatic chromogenic assay. AZ3976 is active with an IC50 of 16 uM in a plasma clot lysis assay. AZ3976 does not bind to active PAI-1 but bound reversibly to latent PAI-1. AZ3976 inhibits PAI-1 by enhancing the latency transition of active PAI-1. AZ3976 displays profibrinolytic activities in a human plasma clot lysis assay.
  • UNSPSC
    12352200

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