AZD7545

MedChem Express

AZD7545 [252017-04-2]

5

252017-04-2

Research Use Only

99.81

C19H18ClF3N2O5S

478.87

AZD7545 is a potent, competitive, selective PDHK2 (pyruvate dehydrogenase kinase 2) inhibitor with IC 50 s of 36.8 nM, 6.4 nM for PDHK1 and PDHK2 , respectively [1] .

O=C(N(C)C)C1=CC=C(S(=O)(C2=CC=C(NC([C@@](C)(O)C(F)(F)F)=O)C(Cl)=C2)=O)C=C1

-20°C,2°C to 8°C

12352200