BAG3 antibody [N1C1]

GeneTex

BAG3 antibody [N1C1]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.12 mg/ml

Unconjugated

BAG3

BAG cochaperone 3

BAG-3, BIS, CAIR-1, CMD1HH, CMT2JJ, HMND15, MFM6, BAG family molecular chaperone regulator 3, BCL2 associated athanogene 3, BCL2-binding athanogene 3, Bcl-2-binding protein BIS transcript 2, bcl-2-binding protein Bis, docking protein CAIR-1

Rabbit

IgG

BAG family molecular chaperone regulator 3

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203