Barbadin

MedChem Express

Barbadin [356568-70-2]

10

356568-70-2

Research Use Only

98.93

C19H15N3OS

333.41

Barbadin is a novel and selective beta-arrestin/beta2-adaptin interaction inhibitor, has IC 50 values of 19.1?microM for beta-arrestin1 and 15.6?microM for beta-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical beta2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis [1] [2] .

O=C1C(C(C2=CC=C(CC3=CC=CC=C3)C=C2)=CS4)=C4N=CN1N

-20°C

12352200