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Barbadin [356568-70-2]

Barbadin [356568-70-2]

T14498
TargetMol Chemicals
CAS Number356568-70-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.93%
Molecular Weight333.41
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Barbadin [356568-70-2]
  • Delivery Days Customer
    10
  • CAS Number
    356568-70-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Barbadin
  • Estimated Purity
    98.93%
  • Molecular Formula
    C19H15N3OS
  • Molecular Weight
    333.41
  • Scientific Description
    Barbadin is a novel and specific inhibitor of beta-arrestin/beta2-adaptin interaction with an IC50 value of 19.1 microM for beta-arestin1 and 15.6 microM for beta-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic beta2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.
  • Shelf life instruction
    3 years
  • SMILES
    Nn1cnc2scc(-c3ccc(Cc4ccccc4)cc3)c2c1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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