MCF-7 activated with 1 microM Dexamethasone was separated on SDS-PAGE and probed with Monoclonal PA to BAX (MO) CL:2D2 (GTX16119). The antibody was developed with with Alkaline Phosphatase APA Mouse Fab ads HIgG conjugate and an NBT/BCIP substrate. Antibody dilution 5 microg/mL.
MCF-7 activated with 1 microM Dexamethasone was separated on SDS-PAGE and probed with Monoclonal PA to BAX (MO) CL:2D2 (GTX16119). The antibody was developed with with Alkaline Phosphatase APA Mouse Fab ads HIgG conjugate and an NBT/BCIP substrate. Antibody dilution 5 microg/mL.
Bax antibody [2D3]
GTX16119
ApplicationsWestern Blot
Product group Antibodies
ReactivityBovine, Canine, Feline, Human, Rat
TargetBAX
Overview
- SupplierGeneTex
- Product NameBax antibody [2D3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/10000. Predicted molecular weight: 21 kDa. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2D3
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID581
- Target nameBAX
- Target descriptionBCL2 associated X, apoptosis regulator
- Target synonymsapoptosis regulator BAX; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2-associated X protein omega; BCL2L4; bcl2-L-4; bcl-2-like protein 4
- HostMouse
- IsotypeIgG1
- Protein IDQ07812
- Protein NameApoptosis regulator BAX
- Scientific DescriptionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Feline, Human, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203