BAY 61-3606 (hydrochloride) [1615197-10-8]
HY-76474A
CAS Number1615197-10-8
Product group Chemicals
Estimated Purity98.08
Molecular Weight426.86
Overview
- SupplierMedChem Express
- Product NameBAY 61-3606 (hydrochloride) [1615197-10-8]
- Delivery Days Customer14
- CAS Number1615197-10-8
- CertificationResearch Use Only
- Estimated Purity98.08
- Molecular FormulaC20H19ClN6O3
- Molecular Weight426.86
- Scientific DescriptionBAY 61-3606 hydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM . BAY 61-3606 hydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. BAY 61-3606 hydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates. BAY 61-3606 hydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.
- SMILESNC(C1=C(N=CC=C1)NC2=NC(C3=CC(OC)=C(C=C3)OC)=CC4=NC=CN24)=O.Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number1615197-10-8
Molecular Weight426.86
- SizePrice
Product group Chemicals
BAY 61-3606 hydrochlorideORB654781
CAS Number1615197-10-8
Molecular Weight426.861
- SizePrice