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Western Blot Positive WB detected in: Mouse lung tissue All lanes: BBS1 antibody at 1ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 70, 50 kDa Observed band size: 66 kDa
Western Blot Positive WB detected in: Mouse lung tissue All lanes: BBS1 antibody at 1ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 70, 50 kDa Observed band size: 66 kDa
Western Blot Positive WB detected in: Mouse lung tissue All lanes: BBS1 antibody at 1ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 70, 50 kDa Observed band size: 66 kDa

BBS1 Antibody

CSB-PA836736LA01HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetBBS1
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Overview

  • Supplier
    Cusabio
  • Product Name
    BBS1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID582
  • Target name
    BBS1
  • Target description
    Bardet-Biedl syndrome 1
  • Target synonyms
    BBS2L2, BBSome complex member BBS1, BBS2-like protein 2, bardet-Biedl syndrome 1 protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NFJ9
  • Protein Name
    BBSome complex member BBS1
  • Scientific Description
    The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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