BCH001

Biorbyt

BCH001 [384859-58-9]

10

384859-58-9

Research Use Only

C20H15F3N2O5

420.3387

BCH001 is a specific PAPD5 inhibitor that restores telomerase activity and telomere length in dyskeratosis congenita (DC) patient induced pluripotent stem cells. PAPD5 is a noncanonical poly(A) polymerase with an unusual RNA-binding motif.

FC(OC1C([H])=C([H])C2C(C=1[H])=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C([H])N=2)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])(F)F

12352200