Rat tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
![Bcl-XL antibody [HL2038] detects Bcl-XL protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX637939/GTX637939_T-44879_20230106_IHC-P_M_23010400_497.webp "Bcl-XL antibody [HL2038] detects Bcl-XL protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637939/GTX637939_44928_20230120_WB_TPM_watermark_23021401_973.webp "Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.")
![Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637939/GTX637939_44928_20230616_WB_D_C_23062019_449.webp "Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![Bcl-XL antibody [HL2038] detects Bcl-XL protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded cat intestine. Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX637939/GTX637939_44928_20230714_IHC-P_Cat_23081619_585.webp "Bcl-XL antibody [HL2038] detects Bcl-XL protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded cat intestine. Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Bcl-XL antibody [HL2038] detects Bcl-XL protein by immunofluorescent analysis. Sample: MDCK cells were fixed in ice-cold MeOH for 5 min. Green: Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX637939/GTX637939_45278_20240719_ICC_IF_D_24080622_797.webp "Bcl-XL antibody [HL2038] detects Bcl-XL protein by immunofluorescent analysis. Sample: MDCK cells were fixed in ice-cold MeOH for 5 min. Green: Bcl-XL stained by Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Blue: Fluoroshield with DAPI (GTX30920).")
Rat tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Bcl-XL antibody [HL2038] (GTX637939) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Bcl-XL antibody [HL2038]
GTX637939
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Feline, Human, Mouse, Rat
TargetBCL2L1
Overview
- SupplierGeneTex
- Product NameBcl-XL antibody [HL2038]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2038
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID598
- Target nameBCL2L1
- Target descriptionBCL2 like 1
- Target synonymsBCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52, bcl-2-like protein 1, apoptosis regulator Bcl-X, protein phosphatase 1, regulatory subunit 52
- HostRabbit
- IsotypeIgG
- Protein IDQ07817
- Protein NameBcl-2-like protein 1
- Scientific DescriptionThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
- ReactivityCanine, Feline, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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