
Western blot analysis of extracts from Hela, A2780 and 293 cells using BCL-2(Ab-56) Antibody.
BCL2 (Ab-56) Antibody
CSB-PA187601
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBCL2
Overview
- SupplierCusabio
- Product NameBCL2 (Ab-56) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID596
- Target nameBCL2
- Target descriptionBCL2 apoptosis regulator
- Target synonymsapoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl-2; PPP1R50; protein phosphatase 1, regulatory subunit 50
- HostRabbit
- IsotypeIgG
- Protein IDP10415
- Protein NameApoptosis regulator Bcl-2
- Scientific DescriptionSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Ling, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991. Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832. Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688. Huang ST,et al. (2002) FASEB J Jun; 16(8): 825-32. Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203