Bio-Connect

BCL2L10 antibody [N1C3]

GTX113911
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetBCL2L10
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Overview

  • Supplier
    GeneTex
  • Product Name
    BCL2L10 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.51 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10017
  • Target name
    BCL2L10
  • Target description
    BCL2 like 10
  • Target synonyms
    anti-apoptotic protein NrH; apoptosis regulator Bcl-B; bcl2-L-10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCL-B; Boo; death inducer binding to vBcl-2 and Apaf-1; Diva
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9HD36
  • Protein Name
    Bcl-2-like protein 10
  • Scientific Description
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203