BCL2L10 antibody [N2C2], Internal

GeneTex

BCL2L10 antibody [N2C2], Internal

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1.32 mg/ml

Unconjugated

BCL2L10

BCL2 like 10

anti-apoptotic protein NrH; apoptosis regulator Bcl-B; bcl2-L-10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCL-B; Boo; death inducer binding to vBcl-2 and Apaf-1; Diva

Rabbit

IgG

Bcl-2-like protein 10

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203