WB analysis of extracts from COS-7 tissue using GTX55399 Bcr (phospho Tyr360) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
WB analysis of extracts from COS-7 tissue using GTX55399 Bcr (phospho Tyr360) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
Bcr (phospho Tyr360) antibody
GTX55399
Overview
- SupplierGeneTex
- Product NameBcr (phospho Tyr360) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID613
- Target nameBCR
- Target descriptionBCR activator of RhoGEF and GTPase
- Target synonymsALL; BCR, RhoGEF and GTPase activating protein; BCR/FGFR1 chimera protein; BCR1; breakpoint cluster region; breakpoint cluster region protein; CML; D22S11; D22S662; FGFR1/BCR chimera protein; PHL; renal carcinoma antigen NY-REN-26
- HostRabbit
- IsotypeIgG
- Protein IDP11274
- Protein NameBreakpoint cluster region protein
- Scientific DescriptionA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityMonkey
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203