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BDNF antibody

GTX132621
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBDNF
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Overview

  • Supplier
    GeneTex
  • Product Name
    BDNF antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.48 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID627
  • Target name
    BDNF
  • Target description
    brain derived neurotrophic factor
  • Target synonyms
    abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP23560
  • Protein Name
    Brain-derived neurotrophic factor
  • Scientific Description
    The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimers and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Effects of Gryllus bimaculatus and Oxya chinensis sinuosa extracts on brain damage via blood-brain barrier control and apoptosis in mice with pentylenetetrazol-induced epilepsy.
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  • Neuroprotective Effects of Lactobacillus plantarum PS128 in a Mouse Model of Parkinsons Disease: The Role of Gut Microbiota and MicroRNAs.
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  • Environment Enrichment Facilitates Long-Term Memory Consolidation through Behavioral Tagging.
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  • Differentiated HT22 cells as a novel model for in vitro screening of serotonin reuptake inhibitors.
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  • Age-related differences for expression of the nerve-specific proteins after peripheral nerve injury. Obata H et al., 2022 Nov, Exp Ther Med
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  • ERRgamma Ligand Regulates Adult Neurogenesis and Depression-like Behavior in a LRRK2-G2019S-associated Young Female Mouse Model of Parkinsons Disease.
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  • Alteration in peritoneal cells with the chemokine CX3CL1 reverses age-associated impairment of recognition memory.
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  • H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure. Yan F et al., 2022 Apr 19, BMC Cardiovasc Disord
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  • Transcranial Ultrasound Stimulation Reverses Behavior Changes and the Expression of Calcium-Binding Protein in a Rodent Model of Schizophrenia.
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  • BDNF expression in GISTs predicts poor prognosis when associated with PD-L1 positive tumor-infiltrating lymphocytes. Tian GA et al., 2021, Oncoimmunology
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