Belvarafenib

MedChem Express

Belvarafenib [1446113-23-0]

10

1446113-23-0

Research Use Only

99.71

C23H16ClFN6OS

478.93

Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF v600E and C-RAF respectively [1] .

O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C

2°C to 8°C

12352200