Belvarafenib

AbMole BioScience

Belvarafenib

9

1446113-23-0

Chemical

Research Use Only

C23H16ClFN6OS

478.93

Belvarafenib (GDC5573, HM95573, RG6185) is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM, 7 nM and 2 nM for BRAF WT, BRAF(V600E) and CRAF kinases, respectively.

CC1=C(NC(=O)C2=CSC3=C2N=CN=C3N)C4=C(C=C1)C(=NC=C4)NC5=C(F)C(=CC=C5)Cl

4°C, sealed

12352200