Berberine chloride
S2271
CAS Number633-65-8
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameBerberine chloride (NSC 646666) [633-65-8]
- Delivery Days Customer9
- CAS Number633-65-8
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionBerberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
- Storage Instruction-80°C
- UNSPSC51202000
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![Berberine chloride [633-65-8]](https://www.targetmol.com/group3/M00/02/ED/CgoaEGY7QfaEELQsAAAAABtSgjo843.png)
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