![WB analysis of Amyloid beta A4 peptides using GTX40068 beta Amyloid (1-40) antibody [BDI350] at 2 microg/mL. Lane 1: Amyloid beta A4 (1-40) Lane 2: Amyloid beta A4 (1-42) Lane 3: Amyloid beta A4 (1-43) WB analysis of Amyloid beta A4 peptides using GTX40068 beta Amyloid (1-40) antibody [BDI350] at 2 microg/mL. Lane 1: Amyloid beta A4 (1-40) Lane 2: Amyloid beta A4 (1-42) Lane 3: Amyloid beta A4 (1-43)](https://www.genetex.com/upload/website/prouct_img/normal/GTX40068/GTX40068_6_WB_w_23060819_816.webp)
WB analysis of Amyloid beta A4 peptides using GTX40068 beta Amyloid (1-40) antibody [BDI350] at 2 microg/mL. Lane 1: Amyloid beta A4 (1-40) Lane 2: Amyloid beta A4 (1-42) Lane 3: Amyloid beta A4 (1-43)
beta Amyloid (1-40) antibody [BDI350]
GTX40068
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetAPP
Overview
- SupplierGeneTex
- Product Namebeta Amyloid (1-40) antibody [BDI350]
- Delivery Days Customer9
- Antibody SpecificitySpecifically reacts with the C-terminus of Human beta Amyloid 1-40. Does not cross-react with betaAmyloid 1-42.
- Application Supplier NoteWB: 1 microg/ml. ICC/IF: 1-10 microg/ml. ELISA: 0.1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBDI350
- Concentration0.10 mg/ml
- ConjugateUnconjugated
- Gene ID351
- Target nameAPP
- Target descriptionamyloid beta precursor protein
- Target synonymsAAA; ABETA; ABPP; AD1; alpha-sAPP; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; amyloid-beta precursor protein; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; CTFgamma; CVAP; peptidase nexin-II; PN2; PN-II; preA4; protease nexin-II; testicular tissue protein Li 2
- HostMouse
- IsotypeIgG1
- Protein IDP05067
- Protein NameAmyloid-beta A4 protein
- Scientific DescriptionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Histamine H3 Inverse Agonist BF 2649 or Antagonist with Partial H4 Agonist Activity Clobenpropit Reduces Amyloid Beta Peptide-Induced Brain Pathology in Alzheimers Disease.Read more