Immunohistochemistry analysis of paraffin-embedded mouse brain using beta Amyloid Polyclonal Antibody at dilution of 1:300.
beta Amyloid Polyclonal Antibody
E-AB-70168
Product group Antibodies
Overview
- SupplierElabscience
- Product Namebeta Amyloid Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionAbeta derives from APP via proteolytic cleavage by proteases called alpha-,beta- and gamma-secretase. The alpha-secretase cleavage precludes the formation of Abeta,while the beta- and gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP),encoded by APP gene which locate on human chromosome 21q,is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth,neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain,kidney,heart and spleen,but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1).
- UNSPSC12352203



