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beta-Rubromycin [27267-70-5]

HY-122482
MedChem Express
CAS Number27267-70-5
Product group Chemicals
Estimated Purity97.7
Molecular Weight536.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    beta-Rubromycin [27267-70-5]
  • Delivery Days Customer
    5
  • CAS Number
    27267-70-5
  • Certification
    Research Use Only
  • Estimated Purity
    97.7
  • Hazard Information
    h302+h312-h319-h351,p264-p270-p280-p302+p352-p305+p351+p338-p330-p362+p364-p405-p501
  • Molecular Formula
    C27H20O12
  • Molecular Weight
    536.44
  • Scientific Description
    beta-Rubromycin, a quinone antibacterial agent, is a selective HIV-1 reverse transcriptase inhibitor with a Ki of 0.27 microM. beta-Rubromycin is a potent telomerase inhibitor with an IC50 of 3 microM. beta-Rubromycin inhibits the proliferation of both K-562 and HeLa cells with IC50 values of 19.5 microM and 22.7 microM, respectively[1][2].
  • SMILES
    O=C(C(O1)=CC(C=C(CC[C@@]2(OC(C3=O)=C(C(C4=C3C(O)=C(OC)C=C4OC)=O)C2)O5)C5=C6O)=C6C1=O)OC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200