Bexotegrast

Selleck Chemicals

Bexotegrast [2376257-44-0]

9

Research Use Only

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Bexotegrast(PLN-74809) is potent dual selective inhibitor of alphavbeta6 and alphavbeta1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-beta activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

-20°C

51202000