BI-0115

MedChem Express

BI-0115 [4929-23-1]

10

4929-23-1

Research Use Only

99.71

C15H14ClN3O

287.74

BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 microM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain[1].

O=C1N(CCC)C2=CC=CN=C2NC3=CC(Cl)=CC=C13

-20°C,2°C to 8°C

12352200