BI-0115 [4929-23-1]

TargetMol Chemicals

BI-0115 [4929-23-1]

4

4929-23-1

Chemical

Research Use Only

BI-0115

99.69%

C15H14ClN3O

287.74

BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.

3 years

CCCN1c2cccnc2Nc2cc(Cl)ccc2C1=O

-20°C

12352200