BI-D1870 [501437-28-1]
S2843
CAS Number501437-28-1
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameBI-D1870 [501437-28-1]
- Delivery Days Customer9
- CAS Number501437-28-1
- CertificationResearch Use Only
- Scientific DescriptionBI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3bèta, MARK3, CK1 and Aurora B. BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy.
- UNSPSC12352200
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