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ProductsBack/Bid (p15-specific ) antibody
WB analysis of Jurkat cells without added BID (Lanes 1 and 2), with caspase-8 cleaved recombinant human BID (Lane 3), or with caspase-8 cleaved recombinant mouse BID (Lane 4) using either a human BID full length antibody (lane 1) or GTX25498 Bid (p15-specific ) antibody (lanes 2-4). The data show that the human BID (p15) antibody recognizes only the human 15 kDa BID fragment, demonstrating the specificity of the antibody.
WB analysis of Jurkat cells without added BID (Lanes 1 and 2), with caspase-8 cleaved recombinant human BID (Lane 3), or with caspase-8 cleaved recombinant mouse BID (Lane 4) using either a human BID full length antibody (lane 1) or GTX25498 Bid (p15-specific ) antibody (lanes 2-4). The data show that the human BID (p15) antibody recognizes only the human 15 kDa BID fragment, demonstrating the specificity of the antibody.
WB analysis of Jurkat cells without added BID (Lanes 1 and 2), with caspase-8 cleaved recombinant human BID (Lane 3), or with caspase-8 cleaved recombinant mouse BID (Lane 4) using either a human BID full length antibody (lane 1) or GTX25498 Bid (p15-specific ) antibody (lanes 2-4). The data show that the human BID (p15) antibody recognizes only the human 15 kDa BID fragment, demonstrating the specificity of the antibody.

Bid (p15-specific ) antibody

GTX25498
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetBID
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Overview

  • Supplier
    GeneTex
  • Product Name
    Bid (p15-specific ) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    ICC/IF: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID637
  • Target name
    BID
  • Target description
    BH3 interacting domain death agonist
  • Target synonyms
    FP497, BH3-interacting domain death agonist, Human BID coding sequence, apoptic death agonist, desmocollin type 4, p22 BID
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55957
  • Protein Name
    BH3-interacting domain death agonist
  • Scientific Description
    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Alternative Fas-mediated cell death pathway is dependent on the different cleavage patterns of procaspase-8. Li Y et al., 2009 Nov, Mol Cell Biochem
    Read more

Datasheet

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