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Biolaminin 521 LN

Name: Biolaminin 521 LN
SKU: LN521_B36
Availability: BackOrder

LN521

Product group Proteins / Signaling Molecules

Overview

Supplier
BioLamina
Product Name
Biolaminin 521 LN
Delivery Days Customer
9
Certification
Research Use Only
Concentration
0.1 mg/ml
Scientific Description
Biolaminin 521 LN is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free and animal origin-free stem cell culture system. LN521 is animal origin-free to the primary level.
Storage Instruction
-20°C to -80°C
UNSPSC
12352202

Rodin S, Antonsson L, Hovatta O, et al. Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc. 2014,9(10):2354-68. doi: 10.1038/nprot.2014.159
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Laperle A, Hsiao C, Lampe M, et al. α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Stem Cell Reports. 2015,5(2):195-206. doi: 10.1016/j.stemcr.2015.06.009
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Zhang D, Yang S, Toledo EM, et al. Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Sci Signal. 2017,10(493):pii: eaal4165. doi: 10.1126/scisignal.aal4165.
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Lu HF, Chai C, Lim TC, et al. A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells. Biomaterials. 2014,35(9):2816-26. doi: 10.1016/j.biomaterials.2013.12.050
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Miyazaki T, Nakatsuji N, Suemori H. Optimization of slow cooling cryopreservation for human pluripotent stem cells. Genesis. 2014,52(1):49-55. doi: 10.1002/dvg.22725
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Bergström R, Ström S, Holm F, et al. Xeno-free culture of human pluripotent stem cells. Methods Mol Biol. 2011,767:125-36. doi: 10.1007/978-1-61779-201-4_9
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