Biotin Anti-Mouse CD120b Antibody

RD20546F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetTnfrsf1b
Overview
- SupplierReddot Biotech
- Product NameBiotin Anti-Mouse CD120b Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDTR75-54.7
- Concentration0.5 mg/ml
- ConjugateBiotin
- Gene ID21938
- Target nameTnfrsf1b
- Target descriptiontumor necrosis factor receptor superfamily, member 1b
- Target synonymsCD120b; p7; p75; p75 TNFR; p80 TNF-alpha receptor; TN; Tnf; TNF-; TNF receptor beta chain; TNF-a; TNFal; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNF-R; Tnfr-1; Tnfr2; TNF-R2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor type II
- HostHamster
- IsotypeIgG
- Scientific DescriptionCD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-Oe+/- and LT-Oe+/- (also known as TNF-beta). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-Oe+/- or LT-Oe+/- trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203