BIRC5 / Survivin Antibody

LifeSpan BioSciences

BIRC5 / Survivin Antibody

23

Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. It is a member of the inhibitor of apoptosis (IAP) family. The gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and two-color FISH. The Survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. It is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.. ELISA (0.1 - 0.5 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml) Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. It is a member of the inhibitor of apoptosis (IAP) family. The gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and two-color FISH. The Survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. It is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

...

BIRC5

baculoviral IAP repeat containing 5

API4, EPR-1, baculoviral IAP repeat-containing protein 5, apoptosis inhibitor 4, apoptosis inhibitor survivin

Rabbit

IgG

Human

-20°C,2°C to 8°C

12352203