Bisindolylmaleimide I

MedChem Express

Bisindolylmaleimide I [133052-90-1]

10

133052-90-1

Research Use Only

98.66

C25H24N4O2

412.48

Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor ( IC 50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCalpha, PKCbetaI, PKCbetaII, and PKCgamma. Bisindolylmaleimide I is also a GSK-3 inhibitor [1] [2] [3] .

O=C(C(C1=CN(CCCN(C)C)C2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O

2°C to 8°C

12352200