Bisindolylmaleimide I (hydrochloride) [176504-36-2]

MedChem Express

Bisindolylmaleimide I (hydrochloride) [176504-36-2]

10

176504-36-2

Research Use Only

98.44

C25H25ClN4O2

448.94

Bisindolylmaleimide I (GF109203X) hydrochloride is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCalpha, PKCbetaI, PKCbetaII, and PKCgamma. Bisindolylmaleimide I hydrochloride is also a GSK-3 inhibitor[1][2][3].

[H]Cl.O=C(C(C1=CN(CCCN(C)C)C2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O

-20°C,2°C to 8°C

12352200