Bio-Connect

BL-1249

ORB1089708
Biorbyt
CAS Number18200-13-0
Product group Chemicals
Molecular Weight291.3503826
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Overview

  • Supplier
    Biorbyt
  • Product Name
    BL-1249 [18200-13-0]
  • Delivery Days Customer
    10
  • CAS Number
    18200-13-0
  • Certification
    Research Use Only
  • Molecular Formula
    C17H17N5
  • Molecular Weight
    291.3503826
  • Scientific Description
    BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 microM) than vascular tissue (EC50 of 21.0 microM). BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 microM and 8.0 microM, respectively
  • SMILES
    N1N=NC(C2=CC=CC=C2NC2=CC=CC3CCCCC2=3)=N1
  • UNSPSC
    12352200