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ProductsBack/BLZ-945 [953769-46-5]
Chemical Structure
Chemical Structure
Chemical Structure

BLZ-945 [953769-46-5]

Research Use Only
SYN-1197
SYNkinase
CAS Number953769-46-5
Product group Chemicals
Estimated Purity>95%
Molecular Weight398.5
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Overview

  • Supplier
    SYNkinase
  • Product Name
    BLZ-945 [953769-46-5]
  • Delivery Days Customer
    10
  • CAS Number
    953769-46-5
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C20H22N4O3S
  • Molecular Weight
    398.5
  • Scientific Description
    BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound. - Chemical. CAS: 953769-46-5. Formula: C20H22N4O3S. MW: 398.5. BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000

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