BLZ-945 [953769-46-5]
SYN-1197
CAS Number953769-46-5
Product group Chemicals
Estimated Purity>95%
Molecular Weight398.5
Overview
- SupplierSYNkinase
- Product NameBLZ-945 [953769-46-5]
- Delivery Days Customer10
- CAS Number953769-46-5
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC20H22N4O3S
- Molecular Weight398.5
- Scientific DescriptionBLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound. - Chemical. CAS: 953769-46-5. Formula: C20H22N4O3S. MW: 398.5. BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound.
- Storage Instruction2°C to 8°C
- UNSPSC51202000