BLZ-945

SYNkinase

BLZ-945 [953769-46-5]

10

953769-46-5

Research Use Only

>95%

C20H22N4O3S

398.5

BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound. - Chemical. CAS: 953769-46-5. Formula: C20H22N4O3S. MW: 398.5. BLZ945 is an orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound.

-20°C,2°C to 8°C

51202000