Sotuletinib

MedChem Express

Sotuletinib [953769-46-5]

10

953769-46-5

Research Use Only

99.83

C20H22N4O3S

398.48

Sotuletinib (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs[1].

O=C(C1=NC=CC(OC2=CC=C3N=C(N[C@H]4[C@H](O)CCCC4)SC3=C2)=C1)NC

-20°C,2°C to 8°C

12352200