BMS-1166 hydrochloride
M29255
CAS Number2113650-05-6
Product group Chemicals
Molecular Weight677.57
Overview
- SupplierAbMole BioScience
- Product NameBMS-1166 hydrochloride
- Delivery Days Customer9
- CAS Number2113650-05-6
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC36H34Cl2N2O7
- Molecular Weight677.57
- Scientific DescriptionBMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
- UNSPSC12352200